The specialists in Pharmacognosy, Bioanalysis & Drug Discovery

Research unit "Pharmacognosy, Bioanalysis & Drug Discovery (PBDD)"

About

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The Unit Pharmacognosy, Bioanalysis & Drug Discovery (PBDD) is one of the research units of the Faculty of Pharmacy. Specialized in the study of organic drugs, from plants or biotherapeutics, the PBDD Unit promotes researches in the domain of the development and the analysis of molecules with therapeutical potential. For bioguided fractionation of medicinal plant extracts, analysis and quality control of drugs, biotherapeutic characterization, biomarker research for validation of therapeutical targets, PBDD Unit proposes performant analytical tools such as liquid/gas chromatography, spectroscopic methods (UV-Vis, NIR, Fluorimetry), electrochemistry detectors and mass spectrometry. PBDD Unit is also responsible for the Analytical Platform of the Faculty of Pharmacy

Team

Academic members

 

Prof. Caroline STEVIGNY (Director)
+32 (0) 2 650 51 72
caroline.stevigny@ulb.be
 

Prof. Jacques DUBOIS
+32 (0) 2 650 52 86
jacques.dubois@ulb.ac.be

Prof. Pierre VAN ANTWERPEN
+32 (0) 2 650 52 63
pierre.van.antwerpen@ulb.be 

Prof. Ass.  Kris DE BRAEKELEER 
+32 (0) 2 650 52 39
kris.de.braekeleer@ulb.b

Prof. Ass. Cédric DELPORTE
+32 (0) 2 650 52 77
cedric.delporte@ulb.be

Senior Academic members

 

Prof. Jean NEVE
+32 (0) 2 650 52 70
jean.neve@ulb.ac.be

Prof. Jean-Michel KAUFFMANN
+32 (0) 2 650 52 70
jean.michel.kauffmann@ulb.be

Postodoctoral fellows and Research logistician

 

Dr Marie VANDEPUT
+32 (0) 2 650 52 45
marie.vandeput@ulb.be

Dr Stefanie FRASELLE
+32 (0) 2 650 52 98
stephanie.fraselle@ulb.be

Dr Gaël DE LEENER
+32 (0) 2 650 52 70
gael.de.leener@ulb.be


PhD students

 

Catherine COREMANS
+32 (0) 2 650 53 31
catherine.coremans@ulb.be

Céline DUCHATEAU
+32 (0) 2 650 52 45
celine.duchateau@ulb.be

Yosra HELALI
+32 (0) 2 650 53 31
yosra.helali@ulb.be

Henry MANYA MBONI
+32 (0) 2 650 52 98
henry.manya.mboni@ulb.be

Corenthin MEES
+32 (0) 2 650 52 41
corenthin.mees@ulb.be

Andrea MONTIS
+32 (0) 2 650 52 41 
andrea.montis@ulb.be

Sofia OLIVEIRE RIBEIRO
+32 (0) 2 650 52 98
sofia.marilia.oliveira.ribeiro@ulb.be

Olga ROJO POVEDA
+32 (0) 2 650 52 98
olga.rojo.poveda@ulb.be

Sebastien SINAEVE
+32 (0) 2 650 52 98
sebastien.sinaeve@ulb.be

Administrative, technical, management and / or specialized members :

 

Marie FAES
+32 (0) 2 650 52 81
marie.faes@ulb.be

Alexandre GARCIA DE CASTRO BARR.
+32 (0) 2 650 52 47
Alexandre.Garcia.De.Castro.Barr@ulb.be

Touria LAMKAMI
+32 (0) 2 650 51 76
touria.lamkami@ulb.be

Dr Véronique MEGALIZZI
+32 (0) 2 650 51 74
veronique.megalizzi@ulb.be

Dominique MERTENS
+32 (0) 2 650 52 47
dominique.mertens@ulb.be

Florence REYE
+32 (0) 2 650 52 70
florence.reye@ulb.be
 

Liliane RICHIL
+32 (0) 2 650 51 76
liliane.richil@ulb.be

Olivier VAILLANT
+32 (0) 2 650 52 84
olivier.vaillant@ulb.be


Alumni

 

Dr I. Aldib (2010-2016)

Prof. A. Aziz (1993)

Prof. B. Blankert (2006)

Prof. A. Boukhlouze (1997)

Dr V. Bunel (2009-2014)

Dr C. Claeys (2006-2014)

Dr M. Cortese (2013-2019)

Dr D. Dufour (2011-2018)

Dr G. Jourquin (1999)

Dr B. Lallemand (2006-2012)

Dr A. Nacoulma (2013)

Dr J. Ngezahyo (2016)

Dr C. Noyon (2010-2017)

Dr P. Okuza Ndjolo (2012)

Dr N. Parij (1993-1999)

Dr S. Patris (2007-2014)

Dr C. Petit (1999)

Dr A. Planinc (2013-2016)

Dr R. Boly (2012)

Dr A. Sakira (2013)

Dr A. Sarakbi (2014)

Prof. I. Some (1999)

Prof. F. Souard (2015-2017)

Dr F. Vanderbist (2000)

Dr O. Vosters (2003)

Dr S. Sikdar (2012-2017)

Dr J. Soubhye (2008-2013)

Dr D. Yu (2008)

Skills
  • Analytical chemistry
  • Pharmaceutical analysis and control
  • Pharmacognosy
  • Bioanalytical chemistry
  • Drug discovery
  • Biological drug (Biologics)
  • Pharmaceutical products
  • Pharmacognosic systematic
  • Spectroscopy (NIR/MIR, UV-Vis)
  • Mass spectrometry
  • Liquid and gas chromatography
  • Metabolomics
  • Glycomics
  • Chemometrics
  • Nano-technology
  • Health sciences
  • Pharmacology
  • Foodstuffs chemistry
  • Electrochemistry
Publications
2019

Christian G, Kauffmann JM. Editorial on 60(th) Anniversary of Talanta. Talanta. 2019 Nov 1;204:883. Abstract

Franck T, Aldib I, Zouaoui Boudjeltia K, Furtmüller PG, Obinger C, Neven P, Prévost M, Soubhye J, Van Antwerpen P, Mouithys-Mickalad A, Serteyn D. The soluble curcumin derivative NDS27 inhibits superoxide anion production by neutrophils and acts as substrate and reversible inhibitor of myeloperoxidase. Chem Biol Interact. 2019 Jan 5;297:34-43. Abstract

Cortese M, Delporte C, Dufour D, Noyon C, Chaumont M, De Becker B, Reye F, Rousseau A, Eker OF, Nève J, Piagnerelli M, Boudjeltia KZ, Robaye B, Van Antwerpen P. Validation of a LC/MSMS method for simultaneous quantification of 9 nucleotides in biological matrices. Talanta. 2019 Feb 1;193:206-214. Abstract

Medfai H, Khalil A, Rousseau A, Nuyens V, Paumann-Page M, Sevcnikar B, Furtmüller PG, Obinger C, Moguilevsky N, Peulen O, Herfs M, Castronovo V, Amri M, Van Antwerpen P, Vanhamme L, Zouaoui Boudjeltia K. Human peroxidasin 1 promotes angiogenesis through ERK1/2, Akt, and FAK pathways. Cardiovasc Res. 2019 Feb 1;115(2):463-475. Abstract

Zeng S, Soetaert K, Ravon F, Vandeput M, Bald D, Kauffmann JM, Mathys V, Wattiez R, Fontaine V. Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation. Antimicrob Agents Chemother. 2019 Feb 26;63(3). Abstract

Colin M, Delporte C, Janky R, Lechon AS, Renard G, Van Antwerpen P, Maltese WA, Mathieu V. Dysregulation of Macropinocytosis Processes in Glioblastomas May Be Exploited to Increase Intracellular Anti-Cancer Drug Levels: The Example of Temozolomide. Cancers (Basel). 2019 Mar 22;11(3). Abstract

Rojo-Poveda O, Barbosa-Pereira L, Mateus-Reguengo L, Bertolino M, Stévigny C, Zeppa AG. Effects of Particle Size and Extraction Methods on Cocoa Bean Shell Functional Beverage. Nutrients. 2019 Apr 17;11(4). Abstract

Carvalho A, Viaene J, Vandenbussche G, De Braekeleer K, Masereel B, Wouters J, Souard F, Vander Heyden Y, Van Antwerpen P, Delporte C, Mathieu V. A new potential anti-cancer beta-carboline derivative decreases the expression levels of key proteins involved in glioma aggressiveness: A proteomic investigation. Drug Dev Res. 2019 Sep 9. doi: 10.1002/ddr.21600. Abstract
2018

Tomani JCD, Gainkam LOT, Nshutiyayesu S, Mukazayire MJ, Ribeiro SO, Stevigny C, Frederich M, Muganga R, Souopgui J. An ethnobotanical survey and inhibitory effects on NLRP3 inflammasomes/Caspase-1 of herbal recipes' extracts traditionally used in Rwanda for asthma treatment. J Ethnopharmacol. 2018 Dec 5;227:29-40.

Khalil A, Poelvoorde P, Fayyad-Kazan M, Rousseau A, Nuyens V, Uzureau S, Biston P, El-Makhour Y, Badran B, Van Antwerpen P, Boudjeltia KZ, Vanhamme L. Apoliporotein L3 interferes with endothelial tube formation via regulation of ERK1/2, FAK and Akt signaling pathway. Atherosclerosis. 2018 Dec;279:73-87.

Rodríguez-Gómez R, Vanheuverzwjin J, Souard F, Delporte C, Stevigny C, Stoffelen P, De Braekeleer K, Kauffmann JM. Determination of Three Main Chlorogenic Acids in Water Extracts of Coffee Leaves by Liquid Chromatography Coupled to an Electrochemical Detector. Antioxidants (Basel). 2018 Oct 15;7(10).

Khalil A, Medfai H, Poelvoorde P, Kazan MF, Delporte C, Van Antwerpen P, El-Makhour Y, Biston P, Delrée P, Badran B, Vanhamme L, Boudjeltia KZ. Myeloperoxidase promotes tube formation, triggers ERK1/2 and Akt pathways and is expressed endogenously in endothelial cells. Arch Biochem Biophys. 2018 Sep 15;654:55-69.

Kajouj S, Marcelis L, Mattiuzzi A, Grassin A, Dufour D, Van Antwerpen P, Boturyn D, Defrancq E, Surin M, De Winter J, Gerbaux P, Jabin I, Moucheron C. Synthesis and photophysical studies of a multivalent photoreactive Ru(II)-calix[4]arene complex bearing RGD-containing cyclopentapeptides. Beilstein J Org Chem. 2018 Jul 16;14:1758-1768. doi: 10.3762/bjoc.14.150. eCollection 2018.

Chaumont M, de Becker B, Zaher W, Culié A, Deprez G, Mélot C, Reyé F, Van Antwerpen P, Delporte C, Debbas N, Boudjeltia KZ, van de Borne P. Differential Effects of E-Cigarette on Microvascular Endothelial Function, Arterial Stiffness and Oxidative Stress: A Randomized Crossover Trial. Sci Rep. 2018 Jul 10;8(1):10378.

Chaumont M, Bernard A, Pochet S, Mélot C, El Khattabi C, Reye F, Boudjeltia KZ, Van Antwerpen P, Delporte C, van de Borne P. High-Wattage E-Cigarettes Induce Tissue Hypoxia and Lower Airway Injury: A Randomized Clinical Trial. Am J Respir Crit Care Med. 2018 Jul 1;198(1):123-126.

Vanhamme L, Zouaoui Boudjeltia K, Van Antwerpen P, Delporte C. The other myeloperoxidase: Emerging functions. Arch Biochem Biophys. 2018 Jul 1;649:1-14.

Dufour D, Khalil A, Nuyens V, Rousseau A, Delporte C, Noyon C, Cortese M, Reyé F, Pireaux V, Nève J, Vanhamme L, Robaye B, Lelubre C, Desmet JM, Raes M, Boudjeltia KZ, Van Antwerpen P. Native and myeloperoxidase-oxidized low-density lipoproteins act in synergy to induce release of resolvin-D1 from endothelial cells. Atherosclerosis. 2018 May;272:108-117.

Delporte C, Zouaoui Boudjeltia K, Furtmüller PG, Maki RA, Dieu M, Noyon C, Soudi M, Dufour D, Coremans C, Nuyens V, Reye F, Rousseau A, Raes M, Moguilevsky  N, Vanhaeverbeek M, Ducobu J, Nève J, Robaye B, Vanhamme L, Reynolds WF, Obinger C, Van Antwerpen P. Myeloperoxidase-catalyzed oxidation of cyanide to cyanate: A potential carbamylation route involved in the formation of atherosclerotic plaques? J Biol Chem. 2018 Apr 27;293(17):6374-6386.

Souard F, Delporte C, Stoffelen P, Thévenot EA, Noret N, Dauvergne B, Kauffmann JM, Van Antwerpen P, Stévigny C. Metabolomics fingerprint of coffee species determined by untargeted-profiling study using LC-HRMS. Food Chem. 2018 Apr 15;245:603-612.

Dufour D, Khalil A, Nuyens V, Rousseau A, Delporte C, Noyon C, Cortese M, Reyé F, Pireaux V, Nève J, Vanhamme L, Robaye B, Lelubre C, Desmet JM, Raes M, Boudjeltia KZ, Van Antwerpen P. Data on myeloperoxidase-oxidized low-density lipoproteins stimulation of cells to induce release of resolvin-D1. Data Brief. 2018 Apr 4;18:1160-1171. doi: 10.1016/j.dib.2018.03.131. eCollection 2018 Jun.

Rosière R, Van Woensel M, Gelbcke M, Mathieu V, Hecq J, Mathivet T, Vermeersch M, Van Antwerpen P, Amighi K, Wauthoz N. New Folate-Grafted Chitosan Derivative To Improve Delivery of Paclitaxel-Loaded Solid Lipid Nanoparticles for Lung Tumor Therapy by Inhalation. Mol Pharm. 2018 Mar 5;15(3):899-910.

Mees C, Souard F, Delporte C, Deconinck E, Stoffelen P, Stévigny C, Kauffmann JM, De Braekeleer K. Identification of coffee leaves using FT-NIR spectroscopy and SIMCA. Talanta. 2018 Jan 15;177:4-11. doi: 10.1016/j.talanta.2017.09.056.

Rodríguez-Gómez R, Vandeput M, Zafra-Gómez A, Kauffmann JM. Liquid chromatography-electrochemical detection for the determination of ethoxyquin and its dimer in pear skin and salmon samples. Talanta. 2018 Jan 15;177:157-162.

Soubhye J, van Antwerpen P, Dufrasne F. Targeting Cytosolic Phospholipase A2α for Novel Anti-Inflammatory Agents. Curr Med Chem. 2018;25(21):2418-2447.

Kauffmann JM, Bakirhan NK, Bozal-Palabiyik B, Uslu B, Rodriguez Gomez R, Vandeput M, Ozkan SA. Electrochemical Detectors in Liquid Chromatography: Recent Trends in Pharmaceutical and Biomedical Analysis. Curr Med Chem. 2018;25(33):4050-4065.

2017

Roumeguère T, Van Antwerpen P, Fathi H, Rousseau A, Vanhamme L, Franck T, Costa C, Morelli A, Lelubre C, Hauzeur C, Raes M, Serteyn D, Wespes E, Vanhaeverbeek M, Zouaoui Boudjeltia K. Relationship between oxidative stress and erectile function. Free Radic Res. 2017 Dec;51(11-12):924-931.

Roumeguère T, Sfeir J, El Rassy E, Albisinni S, Van Antwerpen P, Boudjeltia KZ, Farès N, Kattan J, Aoun F. Oxidative stress and prostatic diseases. Mol Clin Oncol. 2017 Nov;7(5):723-728.

Ngezahayo J, Ribeiro SO, Fontaine V, Hari L, Stévigny C, Duez P. In vitro Study of Five Herbs Used Against Microbial Infections in Burundi. Phytother Res. 2017 Oct;31(10):1571-1578.

Cheraft-Bahloul N, Husson C, Ourtioualous M, Sinaeve S, Atmani D, Stévigny C, Nortier JL, Antoine MH. Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury. J Ethnopharmacol. 2017 Sep 14;209:248-254.

Planinc A, Dejaegher B, Vander Heyden Y, Viaene J, Van Praet S, Rappez F, Van Antwerpen P, Delporte C. Batch-to-batch N-glycosylation study of infliximab, trastuzumab and bevacizumab, and stability study of bevacizumab. Eur J Hosp Pharm. 2017 Sep;24(5):286-292.

Soubhye J, Chikh Alard I, Aldib I, Prévost M, Gelbcke M, De Carvalho A, Furtmüller PG, Obinger C, Flemmig J, Tadrent S, Meyer F, Rousseau A, Nève J, Mathieu V, Zouaoui Boudjeltia K, Dufrasne F, Van Antwerpen P. Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure. J Med Chem. 2017 Aug 10;60(15):6563-6586.

Rasamiravaka T, Ngezahayo J, Pottier L, Ribeiro SO, Souard F, Hari L, Stévigny C, Jaziri ME, Duez P. Terpenoids from Platostoma rotundifolium (Briq.) A. J. Paton Alter the Expression of Quorum Sensing-Related Virulence Factors and the Formation of Biofilm in Pseudomonas aeruginosa PAO1. Int J Mol Sci. 2017 Jun 14;18(6). pii: E1270.

Gau J, Prévost M, Van Antwerpen P, Sarosi MB, Rodewald S, Arnhold J, Flemmig J. Tannins and Tannin-Related Derivatives Enhance the (Pseudo-)Halogenating Activity of Lactoperoxidase. J Nat Prod. 2017 May 26;80(5):1328-1338.

Noyon C, Roumeguère T, Delporte C, Dufour D, Cortese M, Desmet JM, Lelubre C, Rousseau A, Poelvoorde P, Nève J, Vanhamme L, Boudjeltia KZ, Van Antwerpen P. The presence of modified nucleosides in extracellular fluids leads to the specific incorporation of 5-chlorocytidine into RNA and modulates the transcription and translation. Mol Cell Biochem. 2017 May;429(1-2):59-71.

Chopard B, de Sousa DR, Lätt J, Mountrakis L, Dubois F, Yourassowsky C, Van Antwerpen P, Eker O, Vanhamme L, Perez-Morga D, Courbebaisse G, Lorenz E, Hoekstra AG, Boudjeltia KZ. A physical description of the adhesion and aggregation of platelets. R Soc Open Sci. 2017 Apr 12;4(4):170219.

Planinc A, Dejaegher B, Heyden YV, Viaene J, Van Praet S, Rappez F, Van Antwerpen P, Delporte C. LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins. Anal Bioanal Chem. 2017 Jan;409(2):477-485.

2016

Coming soon

2015

Coming soon

Collaborations
National
  • S. Bousbata, ULB, Faculty of Sciences, IBMM
  • E. Cogan, ULB, Faculty of Medicine, Internal Medicine, CHU Erasme
  • F. Corraza, LHUB, CHU Brugmann
  • P. Durez, UCL, Rhumatology Department, CHU Saint-Luc
  • E. Goormaghtigh, ULB, Faculty of Sciences, SFMB Laboratory
  • C. Govaerts, ULB, Faculty of Sciences, SFMB Laboratory
  • P. Jacobs, PharmaFluidics, Ghent
  • D. Mangelings, VUB, Department of Analytical Chemistry and Pharmaceutical Technology, FABI
  • A. Marchant, ULB, IMI
  • J. Nortier, ULB, Faculty of Medicine, Nephrology Laboratory
  • A. Nzeusseu Toukap, UCL, Rhumatology Department, CHU Saint-Luc
  • M. Piagnerelli, ULB, Experimental Medicine Laboratory of CHU Vésale
  • M. Raes, UNamur, Namur Research Institute for Life Sciences (Narilis)
  • T. Roumeguère, ULB, Faculty of Medicine, Urology Department, CHU Erasme
  • J.-M. Ruysschaert, ULB, Faculty of Sciences, SFMB Laboratory
  • P. Vanden Borne, ULB, Faculty of Medicine, Internal Medicine, CHU Erasme
  • Y. Vander Heyden, VUB, Department of Analytical Chemistry and Pharmaceutical Technology, FABI
  • A. Van Eeckhaut, VUB, Department of Pharmaceutical Chemistry and Drug Analysis, Center for Neurosciences (C4N)
  • L. Vanhamme, ULB, Faculty of Sciences, IBMM
  • N. Verbruggen, ULB, Faculty of Sciencses, LPGMP
  • K. Zouaoui Boudjeltia, ULB, Experimental Medicine Laboratory of CHU Vésale
Europe
  • J. Bones, National Institute of Bioprocessing Research and Training, NIBRT, Ireland
  • F. Foulquier, Univesité de Lille 1, UGSF, Villeneuve d’Ascq, France
  • E. Malle, Medical University of Graz, Austria
  • S. Millan-Martin, National Institute of Bioprocessing Research and Training, NIBRT, Ireland
  • W. Morelle, Univesité de Lille 1, UGSF, Villeneuve d’Ascq, France
  • C. Obinger, Department of Chemistry, Division of Biochemistry, BOKU, University of Natural Resources and Applied Sciences, Vienna, Austria
  • E. Thevenot, CEA Saclay, Laboratory for Data Analysis and Systems' Intelligence, France
America
  • W. Reynolds, Sandford Burnham Prebys Medical Discovery Institute, USA
  • P. Bisch, Instituto de Biofísica Carlos Chagas Filho da Universidade Federal do Rio de Janeiro
Africa
  • A. AmineUniversité Hassan II de Casablanca, Maroc
  • B. Bayala, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
  • A. Boukhlouze, Faculté de Médecine et de Pharmacie, Rabat, Maroc
  • M. Kiendrebeogo, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
  • M. Ouedraogo, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
  • I. Some, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
Thesis
2019

Melissa CORTESE, Développement et validation du dosage de 9 nucléotides par couplage LC-MS/MS pour la recherche dans les maladies cardiovasculaires.

2018

Damien DUFOUR, Résolvine D1, cause ou conséquence des interactions entre macrophages et cellules endothéliales ?

2017

Caroline NOYON, La présence intrigante de la myéloperoxydase dans les cellules épithéliales de la prostate, serait-elle impliquée dans les lésions prostatiques ?

Sohely SIKDAR, Evaluation des effets du sulforaphane, de ses dérivés de synthèse et de l’acide α-lipoïque sur plusieurs systèmes de détoxification de modèles expérimentaux du vieillissement cellulaire cutané.

2016

Iyas ALDIB, Rational drug design approach of the myeloperoxidase inhibition: From in silico to pharmacological activity.

Ana PLANINC, Detection of changes in n-glycosylation profiles of therapeutic glycoproteins using LC-MS.

Jeremie NGEZAHAYO, Plantes médicinales du Burundi et maladies infectieuses: enquête ethnobotanique et activités antibactériennes directe et indirecte de composés isolés de Platostoma rotundifolium (Briq.) A. J. Paton (Lamiaceae).

Before 2016

Raïnatou BOLY, Caractérisation des propriétés anti-inflammatoires et anticancéreuses de la plante Agelanthus dodoneifolius (DC) Polh. & Wiens (Loranthaceae) utilisée en médecine traditionnelle au Burkina Faso.

Valérian BUNEL, Recherche de nouvelles substances naturelles d'intérêt dans la prévention de la fibrose rénale d'origine médicamenteuse.

Coraline CLAYES, Contribution à l'étude de la continuité des traitements médicamenteux des patients lors de leur sortie de l'hôpital.

Cédric DELPORTE, Etude des modifications de l'apolipoprotéine B-100 induites par la myéloperoxydase à l'aide de la chromatographie liquide couplée à la spectrométrie de masse.

Benjamin LALLEMAND, Development of novel anticancer glycyrrhetinic acid derivatives with marked anti tumor activity: synthesis and pharmacological evaluation of their activity.

Aminata NACOULMA, Reprogrammation métabolique induite dans les tissus hyperplasiques formés chez le tabac infecté par Rhodococcus fascians: aspects fondamentaux et applications.
​​​
Philippe OKUSA NDJOLO, Etude phytochimique et activité antimicrobienne directe et indirecte de Cordia gilletii De Wild, Boraginaceae.

Nathalie PARIJ, Contribution à l'étude du pouvoir antioxydant des antiinflammatoires non stéroidiens.

Stéphanie PATRIS, Développement d'immunoessais associés aux électrodes sérigraphiées: des particules superparamagnétiques aux nanobodies.

Abdoul Karim SAKIRA, Contribution au développement d’électrodes miniaturisées pour le dosage de métaux lourds à l’état de trace dans les eaux de consommation.

Touridomo Issa SOME, Contribution à l'amélioration de modèles pour estimer les paramètres de stabilité de substances médicamenteuses : cas particuliers de l'acide acétylsalicylique

Jalal SOUBHYE, Design, synthesis and study of myeloperoxidase inhibitors in the series of 3-alkylindole.

Ahmad SARAKBI, Contribution to the development of electrochemical methods for liquid chromatographic analysis and drug quality monitoring.

Pierre VAN ANTWERPEN, Contribution à l'étude du pouvoir antioxydant de divers agents d’intérêt thérapeutique: Ciblage du système myéloperoxydase / peroxyde d'hydrogène / chlorure.

Francis VANDERBIST, Développement, optimisation et évaluation d'une formulation de nacystelyn, un nouvel agent mucoactif sous forme de poudre pour inhalation

Olivier VOSTERS, Contribution à l'étude du pouvoir antioxidant et des propriétés immunomodulatrices d'un composé à groupement thiol, le nacystelyn

Contacts

Université Libre de Bruxelles
Faculty of Pharmacy
Plaine campus, CP 205/09
Building BC - Levels 7
Boulevard de Triomphe, access 2
1050 Brussels
Belgium
Phone : +32 (0) 2 650 51 72 or +32 (0) 2 650 52 81
Fax :+32 (0) 2 650 54 30
Email: caroline.stevigny@ulb.be

Updated on December 19, 2019