Pharmacognosy, Bioanalysis and Drug Discovery (PBDD)

The Unit Pharmacognosy, Bioanalysis & Drug Discovery (PBDD) is one of the research units of the Faculty of Pharmacy. Specialized in the study of organic drugs, from plants or biotherapeutics, the PBDD Unit promotes researches in the domain of the development and the analysis of molecules with therapeutical potential. For bioguided fractionation of medicinal plant extracts, analysis and quality control of drugs, biotherapeutic characterization, biomarker research for validation of therapeutical targets, PBDD Unit proposes performant analytical tools such as liquid/gas chromatography, spectroscopic methods (UV-Vis, NIR, Fluorimetry), electrochemistry detectors and mass spectrometry. PBDD Unit is also responsible for the Analytical Platform of the Faculty of Pharmacy. 

Academic members

Senior Academic members

Postodoctoral fellows

PhD students

Administrative, technical, management and / or specialized members : 

Alumni

2025

Parsajoo YC, Delporte C, Zouaoui Boudjeltia K, Kauffmann JM, Van Antwerpen P. Immobilization of human myeloperoxidase on silica gel for inhibitors assessment (2025) J Pharm Biomed Anal. 2025 Oct 15:264:116974. Abstract

Piron, A., Szymczak, F., Folon, L., Crouch, D.J.M., Papadopoulou, T., Lytrivi, M., Tong, Y., Alvelos, M.I., Colli, M.L., Yi, X., Pekalski, M.L., Hatzikotoulas, K., Huerta-Chagoya, A., Taylor, H.J., Defrance, M., Todd, J.A., Eizirik, D.L., Mercader, J.M., Cnop, M., Identification of novel type 1 and type 2 diabetes genes by co-localization of human islet eQTL and GWAS variants with colocRedRibbon. Cell Genomics, 2025,101004,ISSN 2666-979X. Abstract

Bande M, Delporte C, Sakira AK, Bourez A, Imbault V, Bisteau X, Sombie C, Some TI, Van Antwerpen P. Development of an analytical model for assessing the adsorptive properties of traditional medicinal formulations from Burkina Faso in relation to snake venom proteins. Toxicon. 2025 Oct;265:108470.  Abstract

Virgilio, E., Tielens ,S., Bonfield, G., Nian, F.S., Sawatani, T., Vinci, C., Govier, M., Montaser, H., Lartigue, R., Arunagiri, A., Liboz, A., Natividade da Silva, F., Lytrivi, M., Papadopoulou, T., Wakeling, M.N., Russ-Silsby, J., Bowman, P., Johnson, M.B., Laver, T.W., Piron, A., Yi, X., Fantuzzi, F., Hendrickx, S., Igoillo-Esteve, M., Santacreu, B.J., Suntharesan, J., Ghildiyal, R., Hegde, D.G., Shah, N.A., Acar, S., Özkaya Dönmez, B., Özkan, B., Mohsin, F., Talaat, I.M., Abbas, M.T., Abbas, O.S., Alghamdi, H.A., Kandemir, N., Flanagan, S.E., Scharfmann, R., Arvan, P., Raoux, M., Nguyen, L., Hattersley, A.T., Cnop, M., De Franco, E.
Recessive TMEM167A variants cause neonatal diabetes, microcephaly and epilepsy syndrome. J Clin Invest. 2025 Sep 9:e195756. Abstract

Bande M, Sakira AK, Zangré NR, Bonkoungou HW, Zoungrana EB, Delporte C, Van Antwerpen P, Somé TI. Ethnobotanical study of traditional antivenom treatments in Burkina Faso.Trop Med Health. 2025 Jul 22;53(1):96. Abstract

de Carvalho MML, Nascimento TSD, Rocha GM, Barbosa LC, Bisch PM, Delporte C, Van Antwerpen P, Ruysschaert JM, Batista PR, Lery LMS. Dual Role for Pld1 in Klebsiella pneumoniae Virulence: Transcriptomics and Proteomics Provide Insights into Direct and Indirect Effects. J Proteome Res. 2025 Jun 6;24(6):2874-2884. Abstract

Ravon F, Berns E, Lambert I, Rens C, Adnet PY, Kiass M, Megalizzi V, Delporte C, Baulard A, Mathys V, Boarbi S, Wauthoz N, Fontaine V. Assessment of Innovative Dry Powders for Inhalation of a Synergistic Combination Against Mycobacterium tuberculosis in Infected Macrophages and Mice. Pharmaceutics (2025). May 27;17(6):705. Abstract

Montis A, Paredes-Orejudo V, Bourez A, Steed J, Stoffelen P, Delporte C, Souard F, Stahl-Zeng J, Van Antwerpen P. Comparison between ZenoTOF 7600 system and QTOF for plant metabolome: an example of metabolomics applied to coffee leaves. Metabolomics. 2025 Jan 20;21(1):15. Abstract

Delporte C, Tremblay-Franco M, Guitton Y, Canlet C, Weber RJM, Hecht H, Price EJ, Klánová J, Joly C, Dalle C, Saint-Vanne J, Thévenot E, Schmitz I, Chéreau S, Dechaumet S, Diémé B, Giacomoni F, Le Corguillé G, Pétéra M, Souard F. Workflow4Metabolomics (W4M): A User-Friendly Metabolomics Platform for Analysis of Mass Spectrometry and Nuclear Magnetic Resonance Data.  Curr Protoc. 2025 Feb;5(2):e70095. Abstract

Duchateau, C., Stévigny, C., Waeytens, J., & Deconinck, E. (2025). Chromatographic and Spectroscopic Analyses of Cannabinoids: A Narrative Review Focused on Cannabis Herbs and Oily Products. Molecules (Print Archive Edition), 30(3), 490. Abstract

Bollen, R., Rojo Poveda, O., Ntumba Katshela, B., Tshimi, E. A., Stévigny, C., Delporte, C., Vandelook, F., Stoffelen, P., Honnay, O. The impact of coffee genotype and processing method on the sensory and metabolite profiles of Robusta coffee (Coffea canephora) (2025). European Food Research and Technology, 1-21. Abstract

Boughaleb, H., Verdoy, R., Pochet, A., Fabian, N., Bella, R., Muruganandam, G., Frédérick, R., Zouaoui Boudjeltia, K., Bourez, A., Delporte, C., Van Antwerpen, P., Robert, A., Haufroid, V., Dewulf, J. P., Balligand, J.-L., & Montiel, V. (2025). Repurposing Bacopa monnieri extracts containing Aquaporin-1 blockers to improve systemic oxidative stress: The BacOxy_I study. Advances in Redox Research, 15, 100126. Abstract

2024

Bollen, R., Rojo-Poveda, O., Verleysen, L., Ndezu, R., Tshimi, E. A., Mavar, H., Ruttink, T., Honnay, O., Stoffelen, P., Stévigny, C., Souard, F., Delporte, C. (2024). Metabolite profiles of green leaves and coffee beans as predictors of coffee sensory quality in Robusta (Coffea canephora) germplasm from the Democratic Republic of the Congo. Applied Food Research, 4(2), 100560. Abstract

Montis, A., Delporte, C., Noda, Y., Stoffelen, P., Stévigny, C., Hermans, C., Van Antwerpen, P., & Souard, F. (2024). Targeted metabolomics and transcript profiling of methyltransferases in three coffee species. Plant science, 345, 112117. Abstract

Beniada,  C., Couturier,  B., Reye,  F., Delporte,  C., Van Antwerpen,  P., Cogan,  E., & De Maertelaer,  V. (2024). Methylprednisolone induced morning lymphocytosis: A prospective study in patients with immune mediated inflammatory disorders. La Revue de Medecine Interne. doi:10.1016/j.revmed.2024.07.010

Cnudde, A., Allely, C. A. C., Biset, N., Champy, P., Fouilhe Sam-Lai, N., Huret, F., Laxson, S., Mercan, A. A., Noukela Noumi, D. P., Michalet, S., Montis, A., Pochet, S., Schils, A., Tangeten, C., Tod, M., Van Antwerpen, P., Vervacke, A., & Souard, F. (2024). BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice. BMC complementary medicine and therapies, 24, 414. Abstract

Cnudde, A., Bourez, A., El Khattabi, C., Van Antwerpen, P., & Souard, F. (2024). No reliable clinical results without a proper description of medicinal herbs: Proper clinical results for medicinal herbs. Archives of pharmacy & pharmacology research. Abstract

Akhtar, Z., Canfyn, M., Vanhee, C., Delporte, C., Adams, E., Deconinck, E. (2024). Evaluating MIR and NIR Spectroscopy Coupled with Multivariate Analysis for Detection and Quantification of Additives in Tobacco Products. Sensors (Basel). 2024 Oct 31;24(21):7018. Abstract
 
Helali, Y., Bourez, A., Marchant, A., Vander Heyden, Y., Van Antwerpen, P., & Delporte, C. (2024). Development and validation of online SPE purification coupled to HILIC-fluorescence-MS analysis for the characterization of N-glycans. Talanta, 270, 125541. Abstract 

Helali, Y., & Delporte, C. (2024). Updates of the current strategies of labeling for N-glycan analysis. Journal of chromatography. B, 1237, 124068. Abstract

Akhtar,  Z., Barhdadi,  S., De Braekeleer,  K., Delporte,  C., Adams,  E., & Deconinck,  E. (2024). Spectroscopy and Chemometrics for Conformity Analysis of e-Liquids: Illegal Additive Detection and Nicotine Characterization. Chemosensors, 12(1), 9. Abstract

Turbant, F., Machiels, Q., Waeytens, J., Wien, F., & Arluison, V. (2024). The Amyloid Assembly of the Bacterial Hfq Is Lipid-Driven and Lipid-Specific. International journal of molecular sciences, 25(3), 1434. Abstract

2023

Grosse, C., Brandt, N., Van Antwerpen, P., Wintjens, R., & Matthijs, S. (2023). Two new siderophores produced by Pseudomonas sp. NCIMB 10586: The anti-oomycete non-ribosomal peptide synthetase-dependent mupirochelin and the NRPS-independent triabactin. Frontiers in microbiology, 14. Abstract

Sun, D., Chasseur, C., Mathieu, F., Lechanteur, J., Van Antwerpen, P., Rasschaert, J., Fontaine, V., & Delporte, C. (2023). Untargeted Metabolomics Approach Correlated Enniatin B Mycotoxin Presence in Cereals with Kashin-Beck Disease Endemic Regions of China. Toxins, 15(9). Abstract

Steenebruggen, F., Jacobs, D., Delporte, C., Van Antwerpen, P., Zouaoui Boudjeltia, K., Biston, P., & Piagnerelli, M. (2023). Hyperbaric oxygenation improve red blood cell deformability in patients with acute or chronic inflammation. Microvascular research, 148, 104534. Abstract

Roumeguere, T., Noyon, C., Van Antwerpen, P., Poelvoorde, P., Bar, I., Abdulsater, F., Rousseau, A., Delporte, C., Vanhamme, L., Vanhaeverbeek, M., Delree, P., & Zouaoui Boudjeltia, K. (2023). Role of Myeloperoxidase in ROS Generation and Inflammation Response on Prostate Epithelial Cells. Inflammation. Abstract

Benabbes, R., Ouahhoud, S., Moueqqit, M., Addi, M., Hano, C., Delporte, C., Nacoulma, A., & Megalizzi, V. (2023). The Major Stilbene Compound Accumulated in the Roots of a Resistant Variety of Phoenix dactylifera L. Activates Proteasome for a Path in Anti-Aging Strategy. Cells, 12(1), 71. Abstract

Manya Mboni, H., Faes, M., Fraselle, S., Compaoré, M., Bakari, S. A., Kahumba, B. J., Duez, P., Lumbu Simbi, J.-B., Stévigny, C. Evaluating phytochemical constituents and in-vitro antiplasmodial and antioxidant activities of Fadogiella stigmatoloba, Hygrophylla auriculata, Hylodesmum repandum, and Porphyrostemma chevalieri extracts (2023). Heliyon, 9, e20103, pp: 1-17. Abstract

Duchateau, C., Stévigny, C., De Braekeleer, K., & Deconinck, E. Characterization of CBD oils, seized on the Belgian market, using infrared spectroscopy: Matrix identification and CBD determination, a proof of concept (2023). Drug Testing and Analysis. doi:10.1002/dta.3583. Abstract

Piron, A., Szymczak, F., Papadopoulou, T., Alvelos, M. I., Defrance, M., Lenaerts, T., L Eizirik, D.L., Cnop, M RedRibbon: A new rank–rank hypergeometric overlap for gene and transcript expression signatures (2023) Life Science Alliance, 7 (2) e202302203. Abstract.

Castellá, M., Blasco-Roset, A., Peyrou, M., Gavaldà-Navarro, A., Villarroya, J., Quesada-Lópe,z T., Lorente-Poch, L., Sancho, J., Szymczak, F., Piron, A., Rodríguez-Fernández, S., Carobbio, S., Goday, A., Domingo, P., Vidal-Pui,g A., Giralt, M., Eizirik, D.L., Villarroya, F., Cereijo, R. Adipose tissue plasticity in pheochromocytoma patients suggests a role of the splicing machinery in human adipose browning (2023) iScience, Volume 26, Issue 6, 106847, ISSN 2589-0042. Abstract

Berbon, M., Martinez, D., Morvan, E., Grélard, A., Kauffmann, B., Waeytens, J., Wien, F., Arluison, V., & Habenstein, B. (2023). Hfq C-terminal region forms a ß-rich amyloid-like motif without perturbing the N-terminal Sm-like structure. Communications Biology, 6(1). Abstract

Turbant, F., Waeytens, J., Blache, A., Esnouf, E., Raussens, V., Wegrzyn, G., Achouak, W., Wien, F., & Arluison, V. (2023). Interactions and Insertion of Escherichia coli Hfq into Outer Membrane Vesicles as Revealed by Infrared and Orientated Circular Dichroism Spectroscopies. International Journal of Molecular Sciences (CD-ROM), 24(14), 11424. Abstract

Waeytens, J., De Meutter, J., Goormaghtigh, E., Dazzi, A., & Raussens, V. (2023). Determination of Secondary Structure of Proteins by Nanoinfrared Spectroscopy. Analytical chemistry, 95(2):621-627. Abstract

Bouraoui, A., Louzada, R. A., Aimeur, S., Waeytens, J., Wien, F., My-Chan Dang, P., Bizouarn, T., Dupuy, C., & Baciou, L. (2023). New insights in the molecular regulation of the NADPH oxidase 2 activity: Negative modulation by Poldip2. Free radical biology & medicine, 199, 113-125. Abstract

2022

Forceville, X., Laviolle, B., Gromadzinska, J., Boutten, A., Van Antwerpen, P., Plouvier, E., Annane, D., & Bellissant, E. (2022). Delayed increase of plasma selenoproteins and absence of side effect induced by infusion of pharmacological dose of sodium selenite in septic shock: Secondary analysis of a multicenter, randomized controlled trial. Journal of trace elements in medicine and biology, 73, 127031. Abstract

Krawczyk, L., Semwal, S., Soubhye, J., Lemri Ouadriri, S., Prévost, M., Van Antwerpen, P., Roos, G., & Bouckaert, J. (2022). Native glycosylation and binding of the antidepressant paroxetine in a low-resolution crystal structure of human myeloperoxidase. Acta Crystallographica Section D: Structural Biology, 78(Pt 9), 1099-1109. Abstract

Sabbe, M., Sawchik, J., Gräfe, M., Wuillaume, F., De Bruyn, S., Van Antwerpen, P., Van Hal, G., Desseilles, M., Hamdani, J., & Malonne, H. (2022). Use and misuse of prescription stimulants by university students: a cross-sectional survey in the french-speaking community of Belgium, 2018. Archives of public health, 80(1), 54. Abstract

Okoro, O., Nie, L., Waeytens, J., Hamidi, M., & Shavandi, A. (2022). Thermochemical Liquefaction of Pomace Using Sub/Supercritical Ethanol: an Integrated Experimental and Preliminary Economic Feasibility Study. Bioenergy Research. Abstract

Turbant, F., Waeytens, J., Campidelli, C., Bombled, M., Martinez, D., Grélard, A., Habenstein, B., Raussens, V., Vélez, M., Wien, F., & Arluison, V. (2022). Unraveling Membrane Perturbations Caused by the Bacterial Riboregulator Hfq. International Journal of Molecular Sciences (CD-ROM), 23(15), 8739. Abstract

Forceville, X., Van Antwerpen, P., Annane, D., & Vincent, J. L. (2022). Selenocompounds and Sepsis - Redox Bypass Hypothesis: Part B-Selenocompounds in the Management of Early Sepsis. Antioxidants & redox signalling, 37(13-15), 998-1029. Abstract

Réjasse, A., Waeytens, J., Deniset-Besseau, A., Crapart, N., Nielsen-Leroux, C., & Sandt, C. (2022). Plastic biodegradation: Do Galleria mellonella Larvae Bioassimilate Polyethylene? A Spectral Histology Approach Using Isotopic Labeling and Infrared Microspectroscopy. Environmental science & technology, 56(1), 525-534. Abstract

Raussens, V., & Waeytens, J. (2022). Characterization of Bacterial Amyloids by Nanoinfrared Spectroscopy. In V. Arluison, F. Wien, & A. Marcoleta (Eds.), Characterization of Bacterial Amyloids by Nano-infrared Spectroscopy.(Methods in Molecular Biology, 2538). Abstract

Busi, F., Turbant, F., Waeytens, J., El Hamoui, O., Wien, F., & Arluison, V. (2022). Evaluation of Amyloid Inhibitor Efficiency to Block Bacterial Survival. In Evaluation of Amyloid Inhibitor Efficiency to Block Bacterial Survival.(Methods in Molecular Biology, 2538). Abstract

Sinaeve, S., Husson, C., Antoine, M.-H., Welti, S., Stévigny, C., Nortier, J. Nephroprotective Effects of Two Ganoderma Species Methanolic Extracts in an In Vitro Model of Cisplatin Induced Tubulotoxicity (2022). Journal of Fungi, 8(10), 1002, pp: 1-17. Abstract

Schepers, H. C., Stévigny, C., Duez, P., Kauffmann, J.-M. Editorial: Trends in analytical methods for customs laboratories (2022). Talanta Open, 5, 100110. Link

Montis, A., Souard, F., Delporte, C., Stoffelen, P., Stévigny, C., Van Antwerpen, P. Targeted and Untargeted Mass Spectrometry-Based Metabolomics for Chemical Profiling of Three Coffee Species (2022). Molecules, 27(10), 3152. pp: 1-17. Abstract

Waeytens, J., Turbant, F., Arluison, V., Raussens, V., & Wien, F. (2022). Analysis of Bacterial Amyloid Interaction with Lipidic Membrane by Orientated Circular Dichroism and Infrared Spectroscopies. In Analysis of Bacterial Amyloid Interaction with Lipidic Membrane by Orientated Circular Dichroism and Infrared Spectroscopies.(Methods in Molecular Biology, 2538). Abstract

Ngale Njume, F., Razzauti Sanfeliu, A., Soler García, M., Perschin, V., Fazeli, G., Bourez, A., Delporte, C., Ghogomu Mbigha, S., Poelvoorde, P., Pichard, S., Birck, C., Poterszman, A., Souopgui, J., Van Antwerpen, P., Stigloher, C., Vanhamme, L., & Laurent, P. (2022). A lipid transfer protein ensures nematode cuticular impermeability. iScience, 25(11), 105357. Abstract

Tangeten, C., Zouaoui Boudjeltia, K., Delporte, C., Van Antwerpen, P., & Korpak, K. (2022). Unexpected Role of MPO-Oxidized LDLs in Atherosclerosis: In between Inflammation and Its Resolution. Antioxidants, 11(5), 874. Abstract

Fofana, S., Delporte, C., Calvo Esposito, R., Ouédraogo, M., Van Antwerpen, P., Guissou, I., Semdé, R., & Mathieu, V. (2022). Article In Vitro Antioxidant and Anticancer Properties of Various E. senegalensis Extracts. Molecules, 27(8), 2583. Abstract

Eker, O. F., Lubicz, B., Cortese, M., Delporte, C., Berhouma, M., Chopard, B., Costalat, V., Bonafé, A., Alix-Panabières, C., Van Antwerpen, P., & Zouaoui Boudjeltia, K. (2022). Effects of the flow diversion technique on nucleotide levels in intra-cranial aneurysms: A feasibility study providing new research perspectives. Frontiers in Cardiovascular Medicine, 9, 885426. Abstract
 

2021

Alonso, L., Piron, A., Morán, I., Guindo-Martínez, M., Bonàs-Guarch, S., Atla, G., Miguel-Escalada, I., Royo, R., Puiggròs, M., Garcia-Hurtado, X., Suleiman, M., Marselli, L., Esguerra, J.L.S., Turatsinze, J-V, Torres, J.M., Nylander, V., Chen, J., Eliasson, L., Defrance ,M., Amela, R., Mulder, H., Gloyn, A.L., Groop, L., Marchetti, P., Eizirik, D.L., Ferrer, J., Mercader, J.M., Cnop, M., Torrents, D. TIGER: The gene expression regulatory variation landscape of human pancreatic islets (2021) Cell Reports,Volume 37, Issue 2, 109807, ISSN 2211-1247. Abstract

Duchateau, C., Canfyn, M., Desmedt, B., Kauffmann, J.-M., Stévigny, C., De Braekeleer, K., Deconinck, E. CBD oils on the Belgian market: A validated MRM GC-MS/MS method for routine quality control using QuEChERS sample clean up (2021) Journal of pharmaceutical and biomedical analysis, 205, p. 114344. Abstract

Rojo-Poveda, O., Zeppa, G., Ferrocino, I., Stévigny, C., Barbosa-Pereira, L. Chemometric classification of cocoa bean shells based on their polyphenolic profile determined by rp-hplc-pda analysis and spectrophotometric assays (2021) Antioxidants, 10 (10), art. no. 1533, . Abstract

Deconinck, E., Aït-Kaci, C., Raes, A., Canfyn, M., Bothy, J.-L., Duchateau, C., Mees, C., De Braekeleer, K., Gremaux, L., Blanckaert, P. An infrared spectroscopic approach to characterise white powders, easily applicable in the context of drug checking, drug prevention and on-site analysis (2021) Drug Testing and Analysis, 13 (3), pp. 679-693. Abstract

Forceville, X., Van Antwerpen, P., Preiser, J.-C. Selenocompounds and Sepsis: Redox Bypass Hypothesis for Early Diagnosis and Treatment: Part A - Early Acute Phase of Sepsis: An Extraordinary Redox Situation (Leukocyte/Endothelium Interaction Leading to Endothelial Damage) (2021) Antioxidants and Redox Signaling, 35 (2), pp. 113-138. Abstract

Colin, M., Dechêne, L., Ceusters, J., Niesten, A., Demazy, C., Lagneaux, L., Zouaoui Boudjeltia, K., Franck, T., Van Antwerpen, P., Renard, P., Mathieu, V., Serteyn, D. Priming of mesenchymal stem cells with a hydrosoluble form of curcumin allows keeping their mesenchymal properties for cell-based therapy development (2021) Journal of Cellular and Molecular Medicine, 25 (10), pp. 4877-4881. Abstract

Boufadi, M.Y., Soubhye, J., Van Antwerpen, P. Anti-inflammatory, antioxidant effects, and bioaccessibility of Tigzirt propolis (2021) Journal of Food Biochemistry, 45 (4), art. no. e13663, . Abstract

Ribeiro, S.O., Fraselle, S., Baudoux, D., Zhiri, A., Stévigny, C., Souard, F. Proposals for Antimicrobial Testing Guidelines Applied on Ajowan and Spanish Lavender Essential Oils (2021) Planta Medica, 87 (10-11), pp. 754-763. Abstract

Ribeiro, S.O., Fontaine, V., Mathieu, V., Abdesselam, Z., Dominique, B., Stevigny, C., Souard, F. Antibacterial activities of homemade matrices miming essential oils compared to commercial ones (2021) Antibiotics, 10 (5), art. no. 584. Abstract

Vanhaverbeke, C., Touboul, D., Elie, N., Prévost, M., Meunier, C., Michelland, S., Cunin, V., Ma, L., Vermijlen, D., Delporte, C., Pochet, S., Le Gouellec, A., Sève, M., Van Antwerpen, P., Souard, F. Untargeted metabolomics approach to discriminate mistletoe commercial products (2021) Scientific Reports, 11 (1), 14205. Abstract

De Becker, B., Hupkens, E., Dewachter, L., Coremans, C., Delporte, C., Van Antwerpen, P., Franck, T., Zouaoui Boudjeltia, K., Cullus, P., van de Borne, P. Acute effects of hypouricemia on endothelium, oxidative stress, and arterial stiffness: A randomized, double-blind, crossover study (2021) Physiological Reports, 9 (17), e15018 Abstract

Coremans, C., Delporte, C., Cotton, F., Van De Borne, P., Boudjeltia, K.Z., Van Antwerpen, P. Mass spectrometry for the monitoring of lipoprotein oxidations by myeloperoxidase in cardiovascular diseases (2021) Molecules, 26 (17), 5227 Abstract

Sakira, A.K., Mees, C., De Braekeleer, K., Delporte, C., Yameogo, J., Yabre, M., Some, T.I., Van Antwerpen, P., Mertens, D., Kauffmann, J.M. Determination of the quality of metronidazole formulations by near-infrared spectrophotometric analysis (2021) Talanta Open, 3, Abstract

Rojo-Poveda, O., Ribeiro, S.O., Anton-Sales, C., Keymeulen, F., Barbosa-Pereira, L., Delporte, C., Zeppa, G., Stévigny, C. Evaluation of Cocoa Bean Shell Antimicrobial Activity: A Tentative Assay Using a Metabolomic Approach for Active Compound Identification (2021) Planta Medica, 87 (10-11), art. no. E1330, pp. 841-849. Abstract

Acheampong, A., Mélot, C., Benjelloun, M., Cheval, M., Reye, F., Delporte, C., van Antwerpen, P., Franck, T., Mc Entee, K., van de Borne, P. Effects of hyperoxia and cardiovascular risk factors on myocardial ischaemia–reperfusion injury: a randomized, sham-controlled parallel study (2021) Experimental Physiology, 106 (5), pp. 1249-1262. Abstract

Delporte, C., Noret, N., Vanhaverbeke, C., Hardy, O.J., Martin, J.-F., Tremblay-Franco, M., Touboul, D., Gorel, A., Faes, M., Stévigny, C., Van Antwerpen, P., Souard, F. Does the phytochemical diversity of wild plants like the Erythrophleum genus correlate with geographical origin? (2021) Molecules, 26 (6). Abstract

Montis, A., Souard, F., Delporte, C., Stoffelen, P., Stévigny, C., Van Antwerpen, P. Coffee Leaves: An Upcoming Novel Food? (2021) Planta Medica, 87 (12-13), pp. 949-963. Abstract

Helali, Y., Sharma, S., Vandeput, M., Welba, D., Van Antwerpen, P., Marchant, A., Delporte, C. Fc Glycosylation Characterization of Human Immunoglobulins G Using Immunocapture and LC-MS (2021) Methods in Molecular Biology, 2271, pp. 57-71. Abstract

Derenne, A., Derfoufi, K.-M., Cowper, B., Delporte, C., Butré, C.I., Goormaghtigh, E. Analysis of Glycoproteins by ATR-FTIR Spectroscopy: Comparative Assessment (2021) Methods in Molecular Biology, 2271, pp. 361-374. Abstract

Pireaux, V., Delporte, C., Rousseau, A., Desmet, J.-M., Van Antwerpen, P., Raes, M., Zouaoui Boudjeltia, K. M2 monocyte polarization in dialyzed patients is associated with increased levels of M-CSF and myeloperoxidase-associated oxidative stress: Preliminary results (2021) Biomedicines, 9 (1). Abstract
 

2020

Lytrivi, M., Ghaddar, K., Lopes, M., Rosengren V., Piron A., Yi X., Johansson H., Lehtiö J., Igoillo-Esteve M., Cunha D.A., Marselli L., Marchetti P., Ortsäter H., L. Eizirik D.L., Cnop M. Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity (2020) BMC Genomics 21, 590 . Abstract.

Marsell,i L., Piron, A., Suleiman, M., Colli, M.L., Yi, X., Khamis, A., Carrat, G.R., Rutter, G.A., Bugliani, M., Giusti, L., Ronci, M., Ibberson, M., Turatsinze, J., Boggi, U., De Simone, P., De Tata, V., Lopes, M., Nasteska, D., De Luca, C., Tesi, M., Bosi, E., Singh, P., Campani, D., Schulte, A.M., Solimena, M., Hecht, P., Rady, B., Bakaj, I., Pocai, A., Norquay, L., Thorens, B., Canouil, M., Froguel, P., Eizirik, D.L., Cnop, M., Marchetti, P.
Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes (2020) Cell Reports, Volume 33, Issue 9, 108466, ISSN 2211-1247. Abstract.

González-Vélez, V. , Piron, A., Dupont, G. Calcium Oscillations in Pancreatic α-cells Rely on Noise and ATP-Driven Changes in Membrane Electrical Activity (2020) Frontiers in Physiology, Volume 11, ISSN 1664-042X. Abstract

National

• M. Al Houayek, UCLouvain, Bioanalysis and Pharmacology of Bioactive Lipids Research Group
• R. Bollen, Jardin Botanique de Meise
• S. Bousbata, ULB, Faculty of Sciences, IBMM
• M. Cnop, ULB, Faculty of Medicine, ULB Center for Diabetes Research.
• E. Cogan, ULB, Faculty of Medicine, Internal Medicine, CHU Erasme
• F. Corraza, LHUB, CHU Brugmann
• C. Decock, UCLouvain, Team Mycology
• E. Deconinck, Sciensano, Service Médicaments et produits de Santé
• M. Defrance, ULB, Interuniversity Institute of Bioinformatics in Brussels
• J. Degreef, Jardin Botanique de Meise
• V. Delerck, Jardin Botanique de Meise
• P. Durez, UCL, Rhumatology Department, CHU Saint-Luc
• E. Goormaghtigh, ULB, Faculty of Sciences, SFMB Laboratory
• S. Goriely, ULB, ULB Center for Research in Immunology (U-CRI).
• C. Govaerts, ULB, Faculty of Sciences, SFMB Laboratory
• W. Hubau, African Museum, Head of Wood Biology Service
• P. Jacobs, PharmaFluidics, Ghent
• M. Luhmer, ULB, Cirem plateforme
• D. Mangelings, VUB, Department of Analytical Chemistry and Pharmaceutical Technology, FABI
• A. Marchant, ULB, IMI
• G. Muccioli, UCLouvain, Bioanalysis and Pharmacology of Bioactive Lipids Research Group
• A. Nachtergaël, UMons, Laboratoire de Pharmacognosie et de Chimie thérapeutique
• N. Noret, ULB, Laboratoire d’Ecologie végétale et Biogéochimie
• J. Nortier, ULB, Faculty of Medicine, Nephrology Laboratory
• A. Nzeusseu Toukap, UCL, Rhumatology Department, CHU Saint-Luc
• M. Piagnerelli, ULB, Experimental Medicine Laboratory of CHU Vésale
• M. Raes, UNamur, Namur Research Institute for Life Sciences (Narilis)
• T. Roumeguère, ULB, Faculty of Medicine, Urology Department, CHU Erasme
• J.-M. Ruysschaert, ULB, Faculty of Sciences, SFMB Laboratory
• P. Stoffelen, Jardin Botanique de Meise
  P. Vanden Borne, ULB, Faculty of Medicine, Internal Medicine, CHU Erasme
• Y. Vander Heyden, VUB, Department of Analytical Chemistry and Pharmaceutical Technology, FABI
• A. Van Eeckhaut, VUB, Department of Pharmaceutical Chemistry and Drug Analysis, Center for Neurosciences (C4N)
• L. Vanhamme, ULB, Faculty of Sciences, IBMM
• N. Verbruggen, ULB, Faculty of Sciencses, LPGMP
• K. Zouaoui Boudjeltia, ULB, Experimental Medicine Laboratory of CHU Vésale

Europe

• L. Alonso, Barcelona Supercomputing Center, Life Sciences, Computational Genomics, Spain
• J. Bones, National Institute of Bioprocessing Research and Training, NIBRT, Ireland
• D. Costa Simes, University of Algarve, Faculdade de Ciências e Technologia, Portugal
• F. Foulquier, Univesité de Lille 1, UGSF, Villeneuve d’Ascq, France
• E. Malle, Medical University of Graz, Austria
• S. Millan-Martin, National Institute of Bioprocessing Research and Training, NIBRT, Ireland
• W. Morelle, Univesité de Lille 1, UGSF, Villeneuve d’Ascq, France
• C. Obinger, Department of Chemistry, Division of Biochemistry, BOKU, University of Natural Resources and Applied Sciences, Vienna, Austria
• M. Pękalski, University of Oxford, Nuffield Department of Medicine, Centre for Human Genetics, Diabetes and Inflammation Laboratory (DIL), UK and WIM Research Institute Warsaw, Poland
• E. Thevenot, CEA Saclay, Laboratory for Data Analysis and Systems' Intelligence, France
• J. Todd, University of Oxford, Nuffield Department of Medicine, Centre for Human Genetics, Diabetes and Inflammation Laboratory (DIL), UK
• D. Torrents Arenales, Barcelona Supercomputing Center, Life Sciences, Computational Genomics, Spain
• S. Welti, Université de Lille, Laboratoire de génie civil et de géo-environnement, France
• G. Zeppa, Università degli Studi di Torino, Di.Va.P.R.A., Italy

America

• A. F. Gonzalez, Universidad de la habana, Instituto de Farmacia y Alimentos Cuba
• J. M. Mercader, Broad Institute of MIT and Harvard and Harvard Medical School and Massachusetts General Hospital, USA.
• W. Reynolds, Sandford Burnham Prebys Medical Discovery Institute, USA
• P. Bisch, Instituto de Biofísica Carlos Chagas Filho da Universidade Federal do Rio de Janeiro

Africa

• A. Amine, Université Hassan II de Casablanca, Maroc
• B. Bayala, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
• A. Boukhlouze, Faculté de Médecine et de Pharmacie, Rabat, Maroc
• C. Karangwa, Rwanda Forensic Institute, Rwanda
• M. Kiendrebeogo, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
• J.B. Lumbu Simbi, Université de Lubumbashi, Département de Chimie Organique, RDC
• H. Manya Mboni, Université de Lubumbashi, Laboratoire de Pharmacognosie, RDC
• H. Mavar Manga, Université de Kisangani, RDC
• M. Ouedraogo, Université J. Ki Zerbo, Ouagadougou, Burkina Faso
• I. Some, Université J. Ki Zerbo, Ouagadougou, Burkina Faso

2025

XXX, xxx

2024

Yosra HELALI, Development and validation of a new analytical approach for the characterization of IgG N-glycans in COVID-19, sepsis and HIV infection

Danlei SUN, Study on the connection between mycotoxins and Kashin-Beck Disease in China

2023

Andrea MONTIS, Metabolomics and quantitative RT-qPCR analysis for metabolite profiling of coffee plants: characterization of Coffea anthonyi

Céline DUCHATEAU, Development of analytical methods to study cannabis and derived products

2022

Sofia OLIVEIRA RIBEIRO, Transformation d’huiles essentielles commerciales à visée antibactérienne.

2021

Olga ROJO POVEDA, Valorisation of Compounds with High Nutritional Value from Cocoa By-Products as Food Ingredients and Additives.

2020

Henry MANYA MBONI, Etude de Porphyrostemma chevalieri (O.Hoffm.) Hutch. & Dalziel, une plante réputée antipaludéenne dans la région de Bukavu et d’Uvira (RDC).

2019

Melissa CORTESE, Développement et validation du dosage de 9 nucléotides par couplage LC-MS/MS pour la recherche dans les maladies cardiovasculaires.

2018

Damien DUFOUR, Résolvine D1, cause ou conséquence des interactions entre macrophages et cellules endothéliales ?

2017

Caroline NOYON, La présence intrigante de la myéloperoxydase dans les cellules épithéliales de la prostate, serait-elle impliquée dans les lésions prostatiques ?

Sohely SIKDAR, Evaluation des effets du sulforaphane, de ses dérivés de synthèse et de l’acide α-lipoïque sur plusieurs systèmes de détoxification de modèles expérimentaux du vieillissement cellulaire cutané.

2016

Iyas ALDIB, Rational drug design approach of the myeloperoxidase inhibition: From in silico to pharmacological activity.

Jeremie NGEZAHAYO, Plantes médicinales du Burundi et maladies infectieuses: enquête ethnobotanique et activités antibactériennes directe et indirecte de composés isolés de Platostoma rotundifolium (Briq.) A. J. Paton (Lamiaceae).

Ana PLANINC, Detection of changes in n-glycosylation profiles of therapeutic glycoproteins using LC-MS.

Chantal SHALUKOMA NDUKURA, Diagnostic ethnobotanique partiel des espèces végétales utilisées dans la médecine traditionnelle et par les gorilles de Grauer dans la zone montagneuse de Kahuzi-Biega, RD Congo

Before 2016

Raïnatou BOLY, Caractérisation des propriétés anti-inflammatoires et anticancéreuses de la plante Agelanthus dodoneifolius (DC) Polh. & Wiens (Loranthaceae) utilisée en médecine traditionnelle au Burkina Faso.

Valérian BUNEL, Recherche de nouvelles substances naturelles d'intérêt dans la prévention de la fibrose rénale d'origine médicamenteuse.

Coraline CLAYES, Contribution à l'étude de la continuité des traitements médicamenteux des patients lors de leur sortie de l'hôpital.

Cédric DELPORTE, Etude des modifications de l'apolipoprotéine B-100 induites par la myéloperoxydase à l'aide de la chromatographie liquide couplée à la spectrométrie de masse.

Léocadie KAMAGAJU, Problem of skin depigmentation in Rwanda: modulators of tyrosinase extracted from plants used in traditional medicine.

Benjamin LALLEMAND, Development of novel anticancer glycyrrhetinic acid derivatives with marked anti tumor activity: synthesis and pharmacological evaluation of their activity.

Marie jeanne MUKAZAYIRE, Les plantes médicinales du Rwanda: activités hépatoprotectrices et inhibitrices du virus de l'hépatite C

Aminata NACOULMA, Reprogrammation métabolique induite dans les tissus hyperplasiques formés chez le tabac infecté par Rhodococcus fascians: aspects fondamentaux et applications.
​​​
Philippe OKUSA NDJOLO, Etude phytochimique et activité antimicrobienne directe et indirecte de Cordia gilletii De Wild, Boraginaceae.

Nathalie PARIJ, Contribution à l'étude du pouvoir antioxydant des antiinflammatoires non stéroidiens.

Stéphanie PATRIS, Développement d'immunoessais associés aux électrodes sérigraphiées: des particules superparamagnétiques aux nanobodies.

Abdoul Karim SAKIRA, Contribution au développement d’électrodes miniaturisées pour le dosage de métaux lourds à l’état de trace dans les eaux de consommation.

Touridomo Issa SOME, Contribution à l'amélioration de modèles pour estimer les paramètres de stabilité de substances médicamenteuses : cas particuliers de l'acide acétylsalicylique

Jalal SOUBHYE, Design, synthesis and study of myeloperoxidase inhibitors in the series of 3-alkylindole.

Ahmad SARAKBI, Contribution to the development of electrochemical methods for liquid chromatographic analysis and drug quality monitoring.

Pierre VAN ANTWERPEN, Contribution à l'étude du pouvoir antioxydant de divers agents d’intérêt thérapeutique: Ciblage du système myéloperoxydase / peroxyde d'hydrogène / chlorure.

Francis VANDERBIST, Développement, optimisation et évaluation d'une formulation de nacystelyn, un nouvel agent mucoactif sous forme de poudre pour inhalation

Olivier VOSTERS, Contribution à l'étude du pouvoir antioxidant et des propriétés immunomodulatrices d'un composé à groupement thiol, le nacystelyn

Université Libre de Bruxelles
Faculty of Pharmacy
Plaine campus, CP 205/05
Building BC - Levels 6
Boulevard de Triomphe, access 2
1050 Brussels
Belgium
Phone : +32 (0) 2 650 52 63 
Email: pierre.van.antwerpen@ulb.be