Research in Drug Development (RD3)

Microbiology, Bioorganic and Macromolecular Chemistry

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His research field is the analysis of Biomolecules by InfraRed Spectroscopy and Imaging. This research covers the area of protein aggregation. The first field is the study of protein aggregation mainly in Alzheimer’s disease. The Amyloid beta protein aggregates in the brain into amyloid fibrils. The kinetic of aggregation is not yet known and infrared spectroscopy is well suited to study the aggregation of this protein. It is possible to better understand the structural changes based on the infrared spectra in bulk, but also by the coupling of infrared spectroscopy with atomic force microscopy allowing to study sample at nanoscale. We also apply the Infrared spectroscopy and Imaging technique for other complex sample like tissue sections, fossils or archeological samples.
 

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